PCSIG Webinar On Demand
Finger-prick sampling for the monitoring of tacrolimus, creatinine and hemoglobin in kidney transplant recipients
Finger-prick sampling emerges as an attractive tool for therapeutic drug monitoring and associated diagnostics during follow-up in different patient populations. Kidney transplant recipients constitute a group with likely valuable gain from this concept. It is necessary to meet requirements for quality, efficiency, user-friendliness and new forms of interaction in order to achieve successful implementation in clinical practice. Aspects related to technical operations and quality, factors important for success, as well as identified challenges will be highlighted in this webinar.
Speakers
Nils Tore Vethe
Head of Section, Department of Pharmacology, Oslo University Hospital
Nils Tore Vethe (MScPharm, PhD) is Section Manager at Clinical Pharmacology – Rikshospitalet, Oslo University Hospital. His research focus in recent years has been related to the development of pharmacological methods that can simplify and improve the follow-up of transplant recipients as well as the development of pharmacological tools adapted for patients with cardiovascular diseases. Innovative development of laboratory operations based on analytical methods for self-performed finger-prick sampling, technological modernization supported by automation processes, as well as development and utilization of digital interactions are in the main areas of interest.
Karsten Midtvedt
Senior physician in Nephrology, Department of Transplantation Medicine, Oslo University Hospital
Karsten Midtvedt (MD, PhD) is Senior Physician at the Department of Transplantation Medicine with speciality in nephrology. He has long and extensive experience with follow-up of kidney transplant recipients. His research interests include the development of new tools that facilitate improved follow-up and effective immunosuppressive treatment. He has been the principal investigator with clinical responsibility and led the clinical implementation of therapeutic drug monitoring based on finger-prick sampling in kidney transplant patients.
Moderator
Neil Spooner
Director Spooner Bioanalytical Solutions & Chair Patient Centric Sampling Interest Group
Neil is the co-founder and Chair of the PCSIG. Neil is also the founder of Spooner Bioanalytical Solutions, helping companies to integrate biological fluid microsampling, and patient centric sampling and analysis into workflows. He also works with organizations to develop technologies and introduce them to the market. Neil also assists organizations with their understanding of emerging trends in the pharmaceutical industry and bioanalysis. Neil is a Senior Visiting Research Fellow at the University of Hertfordshire, Editor in Chief of the journal, Bioanalysis and Chair of the Reid Bioanalytical Forum. He has published over 70 peer reviewed manuscripts and delivered over 50 podium presentations.
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Alturas Analytics provides expert GLP & non-GLP LC-MS/MS and GC-MS/MS bioanalytical and PK/TK analysis services of small and large molecules in any matrix for discovery through Phase IV clinical trials.
Capitainer: Dried blood spots (DBS) is now quantitative with volumetric control through our microfluidic qDBS technology solution. Precision, accuracy, sample protection and ease of use both at sampling and in the lab are key features for us in all product development.
Charles River Laboratories are a leading drug discovery and development contract research organization providing a broad spectrum of laboratory and data science support to the clinical development industry. This includes bioanalytical chemistry, immunology, biomarker services, immunoassay, genomics, vaccine development and ADME services. With over 1000 dedicated laboratory colleagues across a global footprint and expertise in traditional and advanced modalities, Charles River Laboratories are well placed to leverage scale and scope to support Clinical programs carried out anywhere in the world.
Genentech: Founded more than 40 years ago, Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious and life-threatening medical conditions. The company, a member of the Roche Group, has headquarters in South San Francisco, California. For additional information about the company, please visit gene.com.
Q Solutions is a leading drug discovery and development laboratory services organization providing innovative solutions that encompass broad central laboratory and specialty biomarker services, including genomics, immunoassays, flow cytometry, anatomic pathology, precision medicine assays, vaccine assays, ADME and bioanalytical along with extensive offerings in antibody drug discovery, biomarker discovery, and decentralized clinical trial lab solutions. Through the Decentralized Clinical Trials group, Q Solutions is at the forefront of patient-centric sampling, offering a variety of self-collection methodologies and is validating multiple assays using micro-samples that are self-collected by study participants.
RedDrop Dx: Next generation blood sampling solutions.
Roche: Doing now what patients need next.
Tasso is an emerging healthcare technology company that is transforming the traditional blood collection paradigm with a patient-centric approach. The company’s devices enable simple, convenient, and virtually painless blood collection for users. Tasso technology has the power to bring healthcare anywhere, any time.
Veloxity Labs is a CRO focused on LC-MS bioanalysis. Our company is employee owned and operated, and offers start-up times and turn-around times in days by maintaining 80% capacity.
Waters Corporation, a global leader in analytical instruments, consumables, and software, has pioneered innovations in chromatography, mass spectrometry, and thermal analysis serving the life sciences market for more than 60 years. Waters Corporation aligns with PCSIG’s mission, supporting collaboration among diverse stakeholders to advance pharmaceutical medicines development and elevating healthcare outcomes and decision-making through analytical innovation and precision.
YourBio Health, makers of the TAP® device, was founded by Flagship Pioneering in 2007. TAP® is the world’s first push button collection device and features patented Halo™ microsampling technology that a enables a patient blood sample to be collected without the pain of a fingerstick or need for traditional phlebotomy. Our patient-centric device is virtually painless, easy-to-use, and enables the collection of a high quality, high volume blood specimen from any setting – clinical or in-home, allowing a more comfortable and less disruptive experience for the patient. We eliminate barriers to blood collection.
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